These findings position the compound as a valuable research tool for investigating whether NNMT modulation influences age-associated metabolic changes in mammalian aging models
These studies employed liposome, bovine serum albumin (BSA), and pBR322 as the models of lipid, protein, and DNA, respectively, to test whether DSePA can prevent radiation-induced lipid peroxidation, protein carbonylation, and strand-breaks
The principal cause of ferroptosis is linked to the peroxidation of PUFAs (Gan, 2022) and PE (Amoscato et al., 2023), while monounsaturated fatty acids inhibit ferroptosis
In another study , high doses of intravenous glutathione resulted in reduced malondialdehyde levels, a marker of liver cell damage
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