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Glutathione lm gin on hot ng ca tyrosinase, mt loi enzyme kim sot vic sn xut qu mc melanin v chuyn sn xut eumelanin (hc sc t) thnh pheomelanin (cc sc t gip da sng hn)

in this case, individuals show a limited or generalized deficiency of GSH and an accumulation of 5-oxoproline (in blood and cerebrospinal fluid) leading to metabolic acidosis [43], mental retardation, neuropsychiatric dysfunction, spinocerebellar degeneration, peripheral neuropathy, myopathy, hepato-splenomegaly, hemolytic anemia, aminoaciduria, and severe neurological complications [134]

On the other hand, viral protein sequences could form complexes with porphyrin, affect heme on the 1- chain of Hb, and release free iron 147

Journal of toxicology

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