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doi: 10.7150/jca.12162 84 FanHKouJHanDLiPZhangDWuQet al

There is an increasing recognition that ASD might be associated with oxidative stress through several mechanisms including abnormal metabolism (lipid peroxidation) and the toxic buildup of reactive oxygen species (ROS)

Monotherapy with rutin or aescin resulted in further improvement, with the HT + Aescin group as evidenced by reduced CK and LDH activities, along with increased AChE activity and decreased DA compared with the hyperthyroid group

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