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Calcium bioavailability and its relation to osteoporosis

However, it is important to note that erythrocytes generate ROS primarily as a result of (i) hemoglobin oxidation, which can be considered as an iron-mediated Fenton reaction, (ii) the activity of NAPDH oxidase and (iii) xanthine oxidoreductase, while in nucleated cells ROS are mainly generated in the mitochondrial electron transport chain

& Watts, J

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studied the effect of the enhanced GPx1 expression against hydroperoxide-, doxorubicin-, and radiation-induced toxicity in the human breast adenocarcinoma cell line (MCF7) [52]