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No evidence of hormonal, hepatic, or cardiovascular adverse effects has been observed in available data

Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate to severe plaque psoriasis over 52 weeks: a phase III, randomized, controlled trial (ESTEEM 2)

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The patient developed shortness of breath, which resulted in an emergency room visit

After a long day of presentations and deliberations, the FDAs Cellular, Tissue, and Gene Therapies Advisory Committee voted overwhelmingly to reject BrainStorm Cell Therapeutics experimental amyotrophic lateral sclerosis (ALS) therapy NurOwn