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257 Strategic booster doses, however, significantly improved cross-protection against variants such as Omicron, highlighting the necessity of age-tailored vaccination protocols

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This metabolic bottleneck places cysteine availability at the center of cellular redox adaptation and makes it a critical determinant of GSH homeostasis under stress conditions

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232,233 In addition to the inactivating mutation of Wnt/-catenin pathway components, abnormal secretion of Wnt ligands in many tumours can also lead to overactivation of the Wnt/-catenin pathway (DKK1, Wnt3a, and Wnt5a)