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Metabolism-dependent hepatotoxicity of amodiaquine in glutathione-depleted mice

Further support for tamoxifen-induced increase in ROS is provided by the decrease in total reduced thiol levels in P-gp-expressing cells and the reversal of its effect on cell growth in the presence of N-acetyl cysteine

About this article Cite this article Melnik, B.C., John, S.M

B.ChaiR.ZhangS.XuS

In some embodiments, the lipid-based drug delivery formulation is a phospholipid-based formulation (e.g., hydrogenated or nonhydrogenated phospholipids, lecithins, phosphatidyl cholines (C8-C18), phosphatidylethanolamines (C8-C18), phosphatidylglycerols (C8-C18)) wherein the phospholipid is phospholipon 90H (1,2-dia-cyl-SN-glycero-3-phosphatidyl choline), egg phospholipids P123, Lipoid E80