To reduce off-target effects, the team applied a double-nicking approach combined with a high-fidelity eCas9 nickase mutant (eCas9n)
Disulfiram octo-arginine-modified lipid emulsions showed a high corneal penetration and a strong effect on delaying selenium-induced cataract generation [107]
[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Sikiric P., Drmic D., Sever M., Klicek R., Blagaic A.B., Tvrdeic A., Kralj T., Kovac K.K., Vukojevic J., Siroglavic M., et al
Patient safety is a top priority, and your healthcare team may adjust your dose or suggest supportive care if needed to ensure that side effects are minimized
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