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Alterations in the gut microbiota have been linked to mood disorders, anxiety and depression, schizophrenia, bipolar disorder, anorexia nervosa and other neuropsychiatric disorders such as Alzheimers disease, Parkinsons disease, autism spectrum disorders and multiple sclerosis [103]

doi: 10.2147/COPD.S391129 36 RouaultTA

10.1093/gerona/glu098 80 GreenbergerJ

Caellas-Socias, A., Sancho, E

The mechanisms of action involve modulation of sleep-regulating neurotransmitters and neuroendocrine systems including enhancement of delta wave activity during deep sleep stages, regulation of cortisol and stress hormone rhythms that impact sleep quality, optimization of circadian rhythm signaling for proper sleep-wake cycles, support for melatonin and sleep-promoting pathways, and modulation of pain perception which can interfere with sleep quality