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There can be tolerance with repeated use, which degrades efficacy and increases doses, leading to safety concerns

Healthy volunteers gave written informed consent in accordance with procedures approved by the local Ethics Committee

A BPD officer may come to 3400 Charles Street and not know exactly where Garland or Ames Hall is, while the JHPD officer is going to know the exact access routes and get to the emergency as fast as possible

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This normalization of cortisol rhythm has downstream effects on mood, energy, appetite, and cognitive function that extend well beyond the sleep period itself