It may provide a unique dietbased intervention to enhance the metabolism of the human body in multiple ways, such as its role as an antioxidant by controlling inflammatory pathways, such as NFB and MAPK, or by regulating other key inflammation markers, such as TNF and IL6
407 In addition, PGC-1 can enhance ATP/ADP translocase activity and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase degradation through proteasome degradation pathway, further restraining ROS generation and apoptosis in endothelial cells
These can lead to a condition called oxidative stress
It has been studied for its stability in acidic environments and its potential role in tissue repair, inflammation control, and wound healing
Since the oxidation of low-density lipoproteins plays an important role in the development of atherosclerosis, the protective effect of carotenoids against cardiovascular diseases has been studied (Kritchevsky 1999)