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Additionally, the TRPM8 gene, which responds to cold stimuli, has been linked to an increased risk of chronic migraine in individuals carrying the TRPM8 rs10166942 T allele (Ling et al., 2019)

doi: 10.1038/s41598-022-11458-4 24 AgnihotriPMonuRamaniSChakrabortyDSaquibMBiswasS

Results May Vary: Individual results will vary based on factors including age, baseline health condition, lifestyle factors, consistency of use, genetic factors, current medications, and other individual variables