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In this, calvariectomy and/or laparotomy (used to assess intracranial (superior sagittal sinus), portal, inferior caval vein and aortal pressure, and brain swelling and organs lesions and vessels presentation) since used in the therapy to counteract increased intracranial pressure and abdominal compartment syndrome [56,57], did not further contribute to the worst circumstances created by the occlusion of the superior sagittal sinus

( e ) Schematic of AKP organoid isolation and culture (3D and 2D cell line) with representative images of 3D or 2D cultures treated 5FU at 72 h

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