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Expression and Role of Gln Transporter in DSMT DSMTs pose a substantial global threat to human health, including colorectal cancer (CRC), gastric cancer (GC), esophageal cancer (EC), pancreatic cancer (PC), and liver cancer (LC)

therefore, drugs targeting EPHB1, PI3K/AKT, and Bcl-2/Bcl-xL, which are involved in the apoptosis resistance pathway, have been developed 28

Gene-specific primers (Supplementary Table S2) were designed using NCBI Primer-BLAST with stringent parameters: amplicon size 90 - 150 bp, melting temperature (Tm) 60 2, and avoidance of secondary structures (OligoAnalyzer Tool, IDT)

Nature Reviews Cancer, 2016, 16(10):619.

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