Bipolar disorder: A landmark RCT (n=75) found that NAC (1,000 mg twice daily for 24 weeks) produced a significant improvement in depression scores (Montgomery-Asberg Depression Rating Scale) in bipolar disorder as an adjunct to usual treatment (Berk et al., Biol Psychiatry, 2008) [74]
The question then arises: What is the explanation for this unique apparent regulation of Se-GSH-Px by organic selenium? Regulation of the GSH-Px system The glutathione (GSH) system, comprising oxidized and reduced GSH and the two enzymes GSH peroxidase and GSH reductase, is closely related to the metabolism of two amino acids, cysteine (Cys) and methionine (Met) (Figure 3) via the key intermediary metabolite, homocysteine
Glutathione acts as your body's natural fire extinguisher, neutralizing inflammatory free radicals
Utility of PET, CT, and EUS to identify pathologic responders in esophageal cancer
Glutathione can also improve skin health by reducing oxidative damage and promoting a brighter, clearer complexion