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While most clinical candidates are described as selective for SLC6A9, few have been comprehensively profiled against the full complement of SLC6 proteins (de Carvalho et al

In IgE-sensitized rat basophilic leukemia cells (RBL-2H3) cell model, apigenin treatment was associated with the suppression of FcRI-mediated activation and downstream MAPK signaling, accompanied by reduced levels of Th2 cytokines (IL-4, IL-5, IL-6, IL-13) and TNF- (Park C.-H

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doi: 10.2337/dc20-1655 100 BapirMUntrachtGRCookeDMcVeyJHSkeneSSCampagnoloPet al