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This phase typically provides the clearest indication of whether the protocol is working for a given individual and condition

doi:10.1016/j.neuroscience.2009.08.028

Always use a fresh syringe and needle for each injection, and properly dispose of used needles in a sharps container

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measured the urinary HS concentration, which may reflect renal glycocalyx degradation, and found that HS was the only glycosaminoglycan that was significantly associated with mortality (hyaluronic acid and chondroitin sulfate were not) and that patients who died of sepsis had significantly higher mean HA concentrations at the start of the study than survivors (112)