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Notable upregulated genes in melatonin-treated ILC2s were components of the molecular circadian clock such as Arntl , along with genes involved in glutathione synthesis such as Gclc ( Figure 5C )

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Additionally, the thiol side chain of cysteines serve as potent nucleophiles and react with oxidants and electrophilic species that would otherwise cause damage to the cell

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C57BL/6Jnia male and female mice, 20 months of age, were obtained from the National Institute on Aging Aged Rodent Colony, contracted by Charles River, Inc