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A 2022 systematic review and meta-analysis published in Frontiers in Endocrinology found that inositol supplementation significantly reduced BMI in women with polycystic ovary syndrome (PCOS), with a pooled weighted mean difference of -0.41 kg/m

Rather than focusing exclusively on a single subpopulation, future development targets could consider the entire population, including children and men

The same disparity between rich animal data and sparse human trials characterizes many peptide compounds, partly because the economics of pharmaceutical development disfavor compounds that cannot be patented in their natural form

[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Satoh T, Kosaka K, Itoh K, Kobayashi A, Yamamoto M, Shimojo Y, Kitajima C, Cui J, Kamins J, Okamoto S, Izumi M, Shirasawa T, Lipton SA

USA 107 , 82378241 (2010)