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Anti-inflammatory peptides typically target more specific pathways NF-kB signaling, mitochondrial ROS, or sirtuin activation which may offer more selective anti-inflammatory effects

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After doublet removal and filtering of the data, we obtained a total of 12,995 adipocyte nuclei (5,874 control, 3,949 Bmal1 KO and 3,172 Bmal1 KO + NDI1) that grouped into five distinct clusters (Fig