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Appetite Effects The question about appetite is interesting because the proposed mechanism could reasonably go either direction: Reduced lipogenesis and improved metabolic flexibility could produce secondary effects on appetite regulation NAD+ restoration has complex effects on hypothalamic appetite signaling Preclinical data do not consistently describe dramatic appetite changes In human use were it to become clinically available patient-reported appetite effects would be a relevant monitoring parameter, but the data do not currently support a strong a priori expectation

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Patients who are pregnant or planning to become pregnant should inform their healthcare provider

The medication further slows gastric emptying, which could exacerbate pre-existing motility issues

Why This Concentration: The Small Cat Precision Argument In cats under 2.5 kg, high-concentration formulations produce injection volumes too small for reliable measurement