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Sans en connatre encore la raison prcise, on remarqua que la prsence du Glutathion permettait de diminuer la toxicit cellulaire , notamment vis--vis de composs aromatiques halogns

10.1111/j.1755-148X.2009.00609.x

3.4 Inhibition of Glutamate Dehydrogenase (GDH) Inhibiting the oxidative deamination of glutamate to -KG has devastating effects on cancer cells comparable to inhibiting glutaminolysis [61, 85]

Then, ductal and mesenchymal cells together with h-HepOrgs were mixed in 1.5 ml DM (without A8301) with 2.4 mg ml 1 methylcellulose, spun down for 5 min at 50 g and incubated for 1824 h at 37 C and 5% CO 2

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