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However, the aspirin-induced decline in ACS2 gene expression was less than 1.5-fold, as opposed to the 2.72-fold downregulation of ACS1

Female patients must have two negative pregnancy tests before starting treatment and are advised to use two forms of birth control or practice abstinence during the six-month period due to the risk of birth defects (this is the purpose of the iPledge program - to prevent unintended pregnancies while taking Accutane)

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Liu Z, Butow RA

Ask for injection training before giving doses at home