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The evidence base is preclinical for IGF-1 LR3 specifically, with adjacent human data from native rhIGF-1 (mecasermin/Increlex)

tHcy concentrations decreased from 19 mol/L and 18 mol/L in the respective groups to around 15 mol/L at days 30 and 90

and founder of the Gapin Institute, a global leader in high performance medicine

There are no clinical studies on compounded tirzepatide + B12 that prove these benefits

Based on the available data, it would not be appropriate to recommend high-dose vitamin intake or substantial changes to typical vitamin intake levels from a balanced diet as a means to reduce cancer risk in the general population