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de Keizer Published: 2017 March Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells Senescent cells accumulate in tissues over time as part of the natural ageing process and the removal of senescent cells has shown promise for alleviating many different age-related diseases in mice

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Figure 1 Under physiological conditions, microglia maintain central nervous system (CNS) homeostasis through a dynamic and context-dependent spectrum of functional states, traditionally described as a balance between pro-inflammatory and protective responses (Tastan and Heneka, 2024)

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