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In MPTPinduced mouse models of PD, structural and functional changes in erythrocyte membranes, including altered lipid microviscosity and disrupted enzyme activity, have been detected during early disease stages [138]

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Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography

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inhibition explored in preclinical metabolic research Oral bioavailability demonstrated in animal models Research Status: 5-Amino-1MQ is in early preclinical stages with limited published research