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Albitar M, Konopleva MY, Zhang H, De Dios I, Ma W, Antzoulatos S, Kornlbau SM, Cavazos A, Loghavi S, Takahashi K, Kantarjian HM, DiNardo CD

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10 ul of each drug solution was added to 90 ul of the rat blood serum samples and at specific time intervals the researchers terminated metabolism by adding 1 ml of ACN and acetic acid in order to precipitate the proteins which were then removed after overnight refrigeration followed by centrifugation

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For context, the ICMR-NIN's 2020 dietary guidelines set the general adult requirement for vitamin C at around 80mg a day for men and 65mg a day for women