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The mice ovulates the same number of MII oocytes, but a lower percentage is morphologically normal, and the yield of zygotes per dam is diminished

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A signal transduction pathway in satratoxin-induced apoptosis in HL-60 cells involves, caspase-3 activation through activation of both caspase-8 and caspase-9 along with cytosolic release of cytochrome c and fragmentation of nucleosomal DNA by DFF-40/CAD [155]

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Interestingly, the shared PPARG locus suggests an effect of metabolic pathways independent of BMI-related pathways