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10.1007/s10620-008-0332-9 130 SkorjanecS.KokotA.DrmicD.RadicB.SeverM.KlicekR.et al (2015)

To enter this pathway, progesterone and 17OHP are 5-reduced by SRD5A1 to yield 5-dihydroprogesterone and 17-hydroxydihydroprogesterone, respectively

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This not only fixes the deficiency but also makes life better for those affected