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Recent studies have shown that at least one mechanism of colchicines action is by acting to prevent a cascade of reactions that lead to the production of interleukin 1-beta, which is an inflammatory protein (cytokine), which is important in gouty inflammation.8 When used as one or two tablets a day (0.6mg each), most people tolerate this medication well, and this dose can help prevent gout attacks

Takahashi S, Mashima K (2022) Neuroprotection and disease modification by astrocytes and microglia in parkinson disease

However, a compelling argument can be made for oral BPC-157

Those with certain genetic variations affecting b12 metabolism may benefit from methylcobalamin specifically

Witch Hazel Water & Aloe Vera: Refreshing base ingredients that tone and hydrate