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A permanent cure for PA is lacking, although repletion of B 12 should be expected to result in a cessation of anemia-related symptoms, a halt in neurological deterioration, and (in cases where neurological problems are not advanced) neurological recovery and a complete and permanent remission of all Symptoms, as long as B 12 is supplemented

Contrasting Preclinical Promise with Human Data The central challenge for clinicians is the stark contrast between the vast, overwhelmingly positive body of preclinical BPC-157 evidence and the near-total absence of published, peer-reviewed human clinical trials

Cell viability assays The cells were plated in triplicate in 96-well plates (4000 cells cultured in 2%FBS DMEM and 2000 cells cultured in 10% FBS DMEM)