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408 In line with this hypothesis, the loss of NAPRT in both RCC cell lines and EMT-subtype gastric cell lines renders the cells hypersensitive to NAMPT inhibitors, such as FK866, and KPT-9274, suggesting that NAMPT inhibitors may be a promising strategy for NAPRT deficient tumors

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The transition should include a washout period of at least 1-2 weeks after the last cagrilintide injection, followed by starting the retatrutide titration from the beginning (1 mg weekly)

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