10.1089/acm.2009.0177 27
The target genes of p53 involve the canonical ferroptosis pathway of GSH metabolism (e.g., SLC7A11), iron metabolism (TfR1 and SLC25A28), lipid metabolism, ROS generation, several oxidation/reduction related proteins, and the non-canonical ferroptosis pathway (66, 67)
CAS 1628202-19-6 Peso molecular 1419.54 (free acid) Frmula C 62 H 98 N 16 O 22 .xC 2 H 4 O 2 SMILES O=C([C@H]1N(CCC1)C([C@H](CCC(O)=O)NC(CN)=O)=O)N2[C@@H](CCC2)C(N3[C@@H](CCC3)C(NCC(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O.[x] Envo Room temperature in continental US
196 : 3750 Jing Y, Dai J, Chalmers-Redman RM, Tatton WG and Waxman S (1999) Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway
Caplan and her staff are very knowledgeable and great at what they do, in my case I worked with Yalda and she was fantastic