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In a study with epileptic rats induced by KA injection into the right CA3 region of the hippocampus, KA administration caused a significant increase in IL- 1 content, as well as a significant increase in MDA concentration and a decrease in GSH level [92]

357,363 In addition, there are mild signs for astrocytic reactivity mainly in cerebral neocortices

Initially, three patients in the loading dose group and seven in the no loading dose group had GDS scores 5, decreasing to two patients in each group by study end

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