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Phase III involves the transport of these metabolites by transporters, after which they are eliminated through bile or urine, preventing potential adverse effects on the liver

Subsequent in vivo evaluation confirmed that the MSC culture conditions that induced high levels of cellular GSH elicited a remarkable regeneration capacity of hES-MSCs at the chondral defect site, suggesting that combining the selection of appropriate cell culture conditions and the FreSHtracer cell sorting method could further potentiate cartilage repair in the chondral defect model

doi: 10.1007/s13318-022-00767-4 50 XuNLuoHLiMWuJWuXChenLet al

Immune cells educated in a dysbiotic gut carry inflammatory memory into the skin and joints

The influence of prenatal fumonisin exposure on bone properties, as well as OPG and RANKL expression and immunolocalization, in newborn offspring is sex and dose dependent