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2010 554 reviews December 29, 2009 Gave up halfway in.....the writing was sparse and did not grab me the way I thought it would and OMG the cliche plot

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Mechanism of Action IGF-1 LR3 and IGF-1 both bind to IGF-1 receptors, the stimulation of which activates pathways, including PI3K/AKT and MAPK, to bring about the following effects: Promotion of glucose uptake and subsequent utilisation Increase in energy production in cells Enhancement of glycolysis Increased protein and lipid synthesis Coordination of nutrient uptake Increase in cell proliferation and differentiation Changes in gene expression that support cell cycle progression and tissue growth

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DSIP represents an interesting case study in peptide research a substance with clear biological activity and intriguing properties that has nonetheless proven difficult to fully characterize and has not achieved mainstream therapeutic development despite decades of investigation