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Not suitable during pregnancy or lactation without medical advice

These cycles are repeated two to four times a year

Ferrari et al

Because these changes occur slowly, they are frequently mistaken for normal aging rather than hormonal imbalances

Am J Physiol Endocrinol Metab 288:E115 Straub SG, Sharp GW (2004) Hypothesis: one rate-limiting step controls the magnitude of both phases of glucose-stimulated insulin secretion