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& Grigorieff, N

Persons afflicted with an inherited form of Wernicke-Korsakoff syndrome appear to have an inborn error of metabolism that is clinically important only when the diet is inadequate in thiamine

2000 Nov;59(4):595600

Indeed, in one hand, their activation is involved in neuroinflammation which endanger neurons via cytokines overproduction and on the other hand, atrophy and loss of activity leads to reduced neuronal protection ( 2+ oscillations than young ones under purinergic stimulation