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The 0.01 mg/kg dose that showed consistent effects in rats translates to approximately 0.0016 to 0.004 mg/kg in humans, which works out to roughly 0.112 to 0.28 mg for a 154-pound person

Excess ROS can damage biomacromolecules, promote pro-inflammatory cytokine release, and skew immune differentiation, potentially exacerbating autoimmune inflammation and tissue injury [34, 35]

Among these stages, hit identification and hit-to-lead optimisation represent critical and resource-intensive bottlenecks, as they define both the chemical viability of candidate molecules and their potential for downstream development 14

C., Rodrguez-Zamora, P., Lpez-Olivos, J

Most patients feel relaxed during the session and may choose to read, scroll on their phone, or simply rest