The Vegan Society and NHS recommend that vegans take B12 supplements or consume fortified foods regularly
When the peptide activates GLP-1 receptors in the brain and digestive system, it sends signals of fullness to the brain and slows down your gastric emptying, which makes you feel satiated with less food and helps in weight loss

Conditions associated with elevated B12 levels include: Liver disease : Hepatocellular damage releases stored B12 into circulation, with levels correlating with disease severity in conditions such as cirrhosis, hepatitis, and hepatocellular carcinoma Renal impairment : Reduced kidney function decreases B12 clearance, leading to accumulation Haematological malignancies : Myeloproliferative disorders, acute leukaemia, and polycythaemia vera can elevate B12 through increased production of B12-binding proteins (transcobalamins) Solid tumours : Certain cancers, particularly those affecting the liver or gastrointestinal tract, may elevate B12 levels A specific concern relates to cyanocobalamin in patients with Leber's hereditary optic neuropathy , a rare mitochondrial disorder
When taking B12 via injections or high doses of supplements, it bypasses the absorption limits of dietary B12, leading to a temporary rise in blood B12 levels
Are B12 injections better than B12 supplements