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This instigated the development of specific small molecule inhibitors of autophagy such as SAR405 or repurposing of FDA approved drugs (254, 292297)
The Paracellular Pathway Cell-to-cell contact between the epithelial cells of the gastrointestinal tract is maintained by tight junction proteins (e.g., occludin, zonula occludens-1, and claudin-2), adherens junction proteins (e.g., E-cadherin), and desmosomes
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