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Vitamin B12, also known as cobalamin, is a crucial nutrient that plays a vital role in various bodily functions

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

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We think that the [neurons influence] on intervertebral disc degeneration is not only limited to the occurrence of pain, but also intervertebral disc degeneration itself, said Ximing Xu, professor in the Department of Orthopedic Surgery in Changzheng Hospital, and co-lead author of the study

Once it receives FDA approval, it will likely be prescribed as a once-weekly injection, much like other medications in the GLP-1 agonist class