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Fine line reduction (weeks 6 to 12): shallow dynamic lines around the eyes and mouth soften as the surrounding matrix becomes better hydrated and structurally supported

Kearns C, Houghton C, Dickinson E, Hatter L, Bruce P, Krishnamoorthy S

10.3390/ijms21217889 139 RenD

Raayachuru, Panvel, Deoghar, Ongole, Nandyal, Morena, Bhiwani, Porbandar, Palakkad, Anand, Purnia, Baharampur, Barmer, Morvi, Orai, Bahraich, Sikar, Vellore, Singrauli, Khammam, Mahesana, Silchar, Sambalpur, Rewa, Unnao, Hugli-Chinsurah, Raiganj, Phusro, Adityapur, Alappuzha, Bahadurgarh, Machilipatnam, Rae Bareli, Jalpaiguri, Bharuch, Pathankot, Hoshiarpur, Baramula, Adoni, Jind, Tonk, Tenali, Kancheepuram, Vapi, Sirsa, Navsari, Mahbubnagar, Puri, Robertson Pet, Erode, Batala, Haldwani-cum-Kathgodam, Vidisha, Saharsa, Thanesar

It also indicates that human loss-of-function mutations in latrophilin-1 (ADGRL1) cause significant neurodevelopmental impairments, underscoring its critical role in neural development [418]