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This gray-market status creates a regulatory vacuum where responsibility for quality, purity, and safety falls to the individual user rather than health authorities

Senescent cells create a pro-inflammatory and pro-fibrotic milieu by releasing Senescence-Associated Secretory Phenotype (SASP) [28]

Both realities need to be understood

Understanding these mechanisms is vital for developing targeted therapies to manage abdominal pain in constipation effectively

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