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Evidence shows that orally administered S.m , along with Veillonella parvula ( V.p , enriched from human subgingival plaque), exacerbated motor dysfunction and neurodegeneration in MPTP-induced PD mice by causing oral and gut dysbiosis, plus brain and systemic immune activation ( Streptococcus subspecies ( S.oralis subsp

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The synergistic effects of these microbial shifts, further potentiated by the anti-inflammatory properties of omega-3 fatty acids, suggest that the Mediterranean diet fosters a holistic anti-inflammatory microbial environment (Nikdasti et al., 2025)

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Darzi S, Alappadan J, Paul K, Mazdumder P, Rosamilia A, Truong YB, et al