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Results were analysed by ANOVA using the GLM procedure of SAS software (SAS institute, 2001) [16]

Consequently, the accumulated NAPQI binds covalently to the cysteine, methionine, tyrosine, and tryptophan residues of various proteins, forming NAPQI-protein adducts within the cell that disrupt normal physiological protein functions

Effects can be mild, moderate, or severe

This facilitates the nuclear translocation of YAP1, subsequently triggering the transcription of ALDH1A1