Vitamin B12 helps convert food into energy, boosts metabolism, and aids in the breakdown of fats and proteins
The 0.01 mg/kg dose that showed consistent effects in rats translates to approximately 0.0016 to 0.004 mg/kg in humans, which works out to roughly 0.112 to 0.28 mg for a 154-pound person
Malmir M, Naderi Noreini S, Ghafarizadeh A, Faraji T, Asali Z
An early study showed that intravenous or intracerebroventricular obestatin had no effects on pituitary hormone release (GH, prolactin, ACTH and TSH) in male rats (116), consistent with the fact that the obestatin receptor GPR39 is not expressed in the pituitary (115,117,118)
doi: 10.1093/jexbot/53.372.1283 52 NoctorG.MhamdiA.ChaouchS.HanY.NeukermansJ.Marquez-GarciaB.et al