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Using caution, however, is warranted, especially since there is no long-term data for humans

Indian J Tradit Knowl 16(1):128133 Tiwari R, Latheef SK, Ahmed I, Iqbal HM, Bule MH, Dhama K, Samad HA, Tiwari R, Verma AK, Kumar A, Dhama K (2012) Immunomodulatory and therapeutic potentials of herbal, traditional/indigenous and ethnoveterinary medicines

607 Clausenamide, an alkaloid isolated from Clausena lansium , interacts directly with Ser663 of ALOX5, blocking the nuclear translocation of ALOX5, alleviating lipid peroxide accumulation and ferroptosis in dopaminergic neurons, significantly improving behavioral deficits in PD mouse models, and providing an attractive strategy for PD treatment

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In this regard, it can be said that both alkaloids/PPs-rich extracts and pure metabolites are influential compounds in the prevention of AFs