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The studies showed a connection between body fat and NNMT levels

Does it work on its own

It has also been reported that 5-amino-1MQ treatment requires an acclimation period, with some subjects reporting decreased exercise tolerance with cardiovascular exercise

Preclinical work in obese murine models suggests that encapsulated 5-Amino-1MQ administration led to decreases in overall body weight and reductions in white adipose mass

Instead, AOD 9604 is used to study downstream metabolic signaling, particularly adipose tissue lipolysis, allowing researchers to isolate lipid metabolism pathways without engaging the broader endocrine GHIGF-1 axis