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In vivo, in conscious swine a model with GH axis pharmacology closely reflective of human GH secretion ipamorelin produced an ED50 of 2.3 0.03 nmol/kg and an Emax of 65 0.2 ng GH/mL plasma, comparable to GHRP-6 (ED50 3.9 1.4 nmol/kg, Emax 74 7 ng/mL) but with substantially superior selectivity

Whole blood samples were assayed for standard cell blood counts with percentage differentials [i.e., hemoglobin, hematocrit, platelet, red blood cell counts, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell distribution width (RDW), white blood cell counts (neutrophils, lymphocytes, monocytes, eosinophils, basophils)